Many people suffer from ulcerative colitis inadvertently. They always think that diarrhea is a trivial matter. They don’t pay much attention to it. Go to the pharmacy to buy some antidiarrheal and anti-inflammatory food, thinking that it’s all right if there is no diarrhea. What is ulcerative colitis? Why is this happening? What negative influence does he have! For ulcerative colitis, everyone often thinks that it is an indeterminate cause and no specific and effective treatment. Ulcerative colitis is a diffuse inflammation of the mucous membranes of the colon and rectum. Its clinical features are bloody diarrhea with unexplained causes and sometimes worsening. In fact, if the disease can be diagnosed in time in the early stage and the treatment of ulcerative colitis is correct, most of them can be cured in a short time.
The reason why ulcerative colitis is difficult to cure is actually this: Many patients regard the disease as hemorrhoids or enteritis, and often take their own medicines and do not go to the doctor; some doctors do not perform necessary examinations. And mistakenly treat hemorrhoids. In addition, some ulcerative colitis has a protracted and recurring course, and doctors and patients therefore lack the confidence to cure the disease.
In fact, the diagnosis of ulcerative colitis is relatively easy. As long as there is continuous blood in the stool and diarrhea, colonoscopy can be performed in time to get the correct diagnosis. The key is to treat ulcerative colitis.
According to recent studies of epidemiology and pathological processes, it is recognized that the adaptive response of the mucosal immune system against aggressive intestinal antigens is the main pathogenesis of ulcerative colitis. For this reason, the main focus of treatment of this disease in recent years is to adopt various methods to quickly close the mucosal inflammatory pathway and block the inflammatory process, so as to achieve the purpose of eliminating the inflammation of the colonic mucosa.
Principles of treatment of ulcerative colitis:
1. Medical treatment. Mild patients take oral medication or use local treatment. Glucocorticoids can be added or switched to moderate patients; enema can be used for those with limited disease. Severe patients can use antibiotics or probiotics as needed. Strengthen supportive treatment. For patients with hormone resistance or hormone tolerance, biological therapy and leukocyte elution therapy can also be considered when conditions permit. Severely ill patients should use antidiarrheal or antispasmodic agents with caution to prevent the induction of toxic megacolon. Patients with severe comorbidities or ineffective medical treatments can be treated with colectomy.
2. A clear diagnosis. Patients diagnosed as mild or moderate are treated with 5-aminosalicylic acid. Choose drugs according to the scope, degree, stage and type of the disease. Refer to previous treatment to choose drugs. Attention should be paid to complications and adverse drug reactions during treatment. Pay attention to systemic therapy and nutritional therapy. Properly master the principles of comprehensive and individualized treatment.
Timing of medication adjustment: the results of colonoscopy should prevail
We found that people mostly reduce the drug dose or stop the drug based on whether the blood in the stool disappears or the symptoms are relieved. In fact, the decrease or disappearance of blood in the stool does not mean that the mucosal inflammation has disappeared. Premature reduction or discontinuation of the drug will cause the disease to repeat.
It should be remembered that being asymptomatic does not mean that the disease is cured, and having symptoms does not mean that the disease is not cured. Adjustment of drug dosage or withdrawal should be based on the results of colonoscopy. In this case, the inflammation of the colonic mucosa is healed, and a period of maintenance treatment with western medicine is required. This is an important part of determining whether the disease will relapse in the future.
Generally speaking, the drug can be discontinued after the initial and mild distal colitis has completely resolved. Other types of UC require maintenance treatment. The main maintenance drug is 5-aminosalicylic acid, and the dose can be half of the remission induction dose. In principle, glucocorticoids are not used for maintenance. Some studies suggest that long-term use of probiotics can reduce the recurrence of the disease, and some individuals are more suitable to take traditional Chinese medicine as a treatment to prevent recurrence. Whether it is treatment in the active phase or maintenance treatment in the remission phase, attention should be paid to the education of patient compliance. Due to the high recurrence rate of ulcerative colitis, patients should be educated to take rest during the recovery period, maintain a stable and happy mood, closely observe changes in the condition, pay attention to the influence of diet, prevent infection, and avoid recurrence of the disease.
Jilin Province Jilin Hospital of Integrated Traditional Chinese and Western Medicine (Jilin City) uses traditional Chinese medicine for oral administration, Chinese medicine for soaking, and Chinese medicine enema. Welcome to consult.