2021年1月26日星期二

preparation h hemorrhoids,Are you afraid of diarrhea?

    Xin Xuezhi Li Deyi Xin Xuezhi The day before yesterday

    In daily life, we often encounter patients with "diarrhea" as the main symptom. Most patients have general inflammatory bowel disease, indigestion, and bacillary dysentery. However, for a small number of patients, the diarrhea does not heal for a long time, but it may be caused by malignant tumors. This requires us to be more vigilant!

    It is worth noting that most of the patients with diarrhea caused by tumors mistakenly believe that they have general gastrointestinal diseases, which are paralyzed and lose valuable treatment opportunities.

    Patients think that "diarrhea" is caused by general intestinal diseases or cold, unsanitary food, etc., so they often buy medicines for treatment at home. Some doctors who lack clinical experience often prescribe medicines for diseases such as "enteritis", but the results are delayed and delayed. Therefore, we must pay attention to find out the cause, and we must not just fight inflammation and stop diarrhea.

    In fact, the digestive system, especially malignant tumors in the gastrointestinal tract, such as gastric cancer, colon cancer, and rectal cancer are prone to diarrhea. However, this type of cancer is easy to attract people's attention, and the misdiagnosis rate is generally not high.

    The most confusing thing is the diarrhea caused by tumors in other parts, which is not easy to cause people to be alert.

    Today, I will give you a brief summary of several tumors that may be related to long-term diarrhea.

    1. Colorectal cancer: Constipation and diarrhea are common in daily life, and these two symptoms may also be signs of bowel cancer.

    Colorectal cancer includes colon cancer and rectal cancer. Its occurrence is mostly related to chronic inflammation of the large intestine, colorectal adenoma, high-fat, low-fiber eating habits, heredity and genes. The early symptoms of colorectal cancer are generally not obvious, but with the development of cancer , Patients will gradually develop symptoms such as abdominal pain, stool bleeding, intestinal obstruction, and abdominal masses.

    Changes in bowel habits and stool characteristics are important indicators for early detection of colorectal cancer.

    Because the tumor and its secretions stimulate the intestines, people who have regular bowel movements will suddenly become frequent or significantly reduced. Constipation and diarrhea alternately appear, morning diarrhea, etc., especially accompanied by mucus and blood in the stool, pus and blood in the stool. , Blood in the stool is bright red or jam-colored. Or when there is unexplained anemia, weight loss, or weakness, you must be more vigilant. When symptoms of colorectal cancer appear, patients must seek medical attention in time.

    In the early stage of bowel cancer, there will be symptoms of blood in the stool, which is particularly easy to be confused with hemorrhoids, causing many patients to be diagnosed at an advanced stage. Colorectal cancer is easy to be misdiagnosed as hemorrhoids in the early stage. More than 70% of colorectal cancer patients are misdiagnosed as hemorrhoids.

    The reason for the high rate of misdiagnosis is that the clinical manifestations of anorectal tumors and hemorrhoids have many similarities, such as blood in the stool and increased stool frequency. In addition, rectal cancer may compress the rectal veins and block the return of blood, which may lead to hemorrhoids. Therefore, the changes in the disease are easily obscured by the appearance of hemorrhoids.

    In fact, these can be avoided. No matter how similar the symptoms are, as long as an anorectal endoscopy is performed, most anorectal tumors can be detected early.

    In addition, there are subtle differences in close observation. For example, if bleeding is caused by hemorrhoids, the blood is separated from the stool; if it is caused by the tumor, the blood and stool are usually mixed together.

    Some patients will also find that the stool is mixed with mucus, just like thick sputum. This is a danger signal, which may be intestinal inflammation, or it may be infection due to ruptured cancer.

    2. Gastric cancer: Gastric cancer ranks first among all kinds of malignant tumors in China. It is mostly related to Helicobacter pylori infection, heredity and genes, eating habits and other factors. Gastric cancer usually has no obvious symptoms in the early stage, which is very similar to general gastroenteritis, diarrhea with nausea, Acid reflux, so it is easy to be ignored.

    If unexplained diarrhea occurs suddenly, black stools are accompanied by loss of appetite, weakness, and symptoms such as nausea, stomach burning, epigastric pain or pain, the possibility of tumors should be considered.

    Especially middle-aged people over the age of 40, as well as people who usually suffer from chronic peptic ulcers, should pay more attention to timely gastroscopy and other investigations.

    Since stomach cancer occurs in the higher part of the abdomen, it usually presents as symptoms of diarrhea. Diarrhea caused by gastric cancer is different from general diarrhea. Diarrhea caused by gastric cancer is usually accompanied by a feeling of upper abdomen pain and constipation. At this time, patients should go to the hospital for gastroscopy in time.

    3. Liver cancer: Liver cancer is usually accompanied by cirrhosis, which can easily lead to portal hypertension or embolism, causing intestinal wall edema, accelerated intestinal peristalsis, digestion and secretion disorders, and diarrhea.

    Studies have shown that about half of primary liver cancers have diarrhea symptoms 3 months before diagnosis, and the number of diarrhea varies from 2 to 20 times each time.

    Therefore, if patients with liver cirrhosis have symptoms of unexplained diarrhea, they must remember to seek medical attention in time.

    Among patients with liver cancer, there are many rare cases with diarrhea as the first symptom. Someone once counted 3254 cases of liver cancer patients and found that diarrhea was the first symptom accounted for 5.8%.

    The cause of diarrhea is that liver cancer cells can produce gastrin, vasoactive peptide, prostaglandin F2 and other substances during the process of division and proliferation. Mast cells will proliferate and release too much histamine after being stimulated by these substances. , Promote the permeability of the intestinal mucosa and blood vessel wall, increase the secretion of intestinal juice and cause diarrhea.

    Therefore, patients with daily diarrhea must not be treated as chronic enteritis or malabsorption syndrome. You should go to the hospital for necessary examinations such as serum alpha-fetoprotein (AFP), B-ultrasound, CT, etc., and make an early diagnosis.

    For middle-aged and elderly people, especially patients with chronic hepatitis or liver cirrhosis, if there is discomfort in the upper right of the abdomen, swelling and pain in the liver area and gradually worsening, or loss of appetite or weight loss, they should go to the hospital for color Doppler ultrasound and liver as soon as possible. Check function, alpha-fetoprotein, etc. to find out the cause.

    4. Islet cell tumors: Islet cell tumors are tumors that occur in islet cells, which are often seen in people between 20 and 50 years old. Islet cell tumors often cause diarrhea due to peptic ulcer disease. Patients generally consume excessive amounts Symptoms of diarrhea after fat and cholesterol, as well as nausea, fatigue, weight loss and other symptoms.

    Because the position of the pancreas is often obscured by the stomach and transverse colon, it is not easy to find pancreatic lesions in ordinary examinations, and the early diagnosis rate of pancreatic cancer is also very low. Some patients with chronic pancreatitis and pancreatic cancer can cause chronic diarrhea due to pancreatic dysfunction.

    Therefore, if there are unexplained upper abdominal discomforts, repeated diarrhea, steatorrhea, indigestion, low back pain, jaundice caused by non-gallstones, unexplained weight loss, etc., you should pay attention to it and seek medical examination in time. .

    Especially high-risk groups with long-term smoking history, chronic pancreatitis, and family history of pancreatic cancer.

    5. Lung cancer and other cancers: studies have shown that certain lung cancer cells can produce various regulatory peptides, such as adrenaline, parathyroid hormone, calcitonin, antidiuretic hormone and serotonin, etc. These hormones directly enter the blood circulation , Make people appear carcinoid syndrome, diarrhea is a prominent symptom.

    In addition, there are medullary thyroid tumors, somatostatinomas, gastrinomas and other malignant tumors that also have diarrhea and indigestion symptoms.

    Diarrhea and diarrhea are very common minor problems, but if accompanied by the above symptoms, do not take it lightly, find out the risk factors of the disease hidden in the body, diagnose the cause in time, and strive to treat the disease as soon as possible.

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