Characteristics of colorectal cancer in young people
1. The early diagnosis rate is very low. Among the diagnosed young people with colorectal cancer, 50% to 80% of patients are already in the middle and advanced stages, and the patients under the age of 20, once diagnosed, are almost all in the middle and advanced stages.
2. High degree of malignancy. The less differentiated the cancer, the higher the malignancy. Among the diagnosed young people’s colorectal cancers, the worst-differentiated mucinous adenocarcinoma accounts for 50% to 60%, which is 3-6 times that of elderly patients; patients younger than 20 years old, mucinous adenocarcinoma accounts for 80% %～90%.
3. Pain symptoms are prominent and easy to bleed. Since most of the patients are in the late stage and are prone to acute intestinal obstruction, about 40% of patients have abdominal pain as the first manifestation. As for bleeding, most patients will not pay attention to it, and will be treated as hemorrhoids for a long time, causing delays in the condition.
4. Female patients with bowel cancer have a high rate of ovarian metastasis. There is a data showing that among the diagnosed young women with colorectal cancer, the ovarian metastasis rate is as high as 12%, and 1/3 of the patients come to the hospital with ovarian tumors.
5. The diagnosis time is long. Generally, it takes about 5 to 10 months for young people with colorectal cancer to have symptoms to be diagnosed by examination, which directly leads to the delay of the disease.
6. The misdiagnosis rate is high. The misdiagnosis rate of colorectal cancer among young people is as high as 78.5%. There are many reasons. For example, doctors are satisfied with the benign diseases that have been discovered and did not perform further examinations; they only pay attention to symptoms and lack a detailed understanding and comprehensive analysis of the medical history; excessive consideration of age factors and lack of understanding and response to young people’s colorectal cancer Some are vigilant and so on.
People who are more likely to get colorectal cancer
1) Age: As the age increases, the time for various pathogenic factors to stimulate the large intestine mucosa also increases, and most patients develop the disease after the age of 50;
2) Family history: If a person's first-degree family members, such as parents, have had colorectal cancer, his risk of developing this disease in his lifetime is 8 times higher than that of the general population. About 1/4 of new patients have a family history of colorectal cancer; 3) History of colitis: Certain colon diseases such as Crohn’s disease or ulcerative colitis may increase the chance of colorectal cancer. Their risk of colon cancer is 30 times that of ordinary people;
4) History of colorectal polyps: Most colorectal cancers develop from small precancerous lesions. They are called polyps. Among them, villous adenoma polyps are more likely to develop into cancer, and the chance of malignant transformation is about 25%; the malignant rate of tubular adenomatous polyps is 1-5%;
5) Genetic background: Familial adenomatous polyposis and hereditary non-polyposis cancer are all caused by mutations in the corresponding genes. Such patients not only have a significantly increased incidence rate, but also have a younger age of onset. 1